Diagnose CIRS, Chronic Inflammatory Response Syndrome, in Australia


CIRS Blood Test

Finally, Australian patients can access specialized blood tests for Chronic Inflammatory Response Syndrome (CIRS), developed by Dr. Ritchie Shoemaker. These tests offer valuable insights for both patients and physicians seeking answers to persistent health problems.

CIRS Blood Test Markers:

  • Elevated: TGF-beta1, C4a, C3a
  • Low: MSH, VIP

These markers can help determine the presence of CIRS, a condition often linked to hidden microbial exposures in homes, workplaces, or other environments.

Understanding the Science Behind the CIRS Blood Test:

  • Decreased MSH and VIP: These neuropeptides help regulate the immune system. Their decline in CIRS patients contributes to inflammation.
  • Elevated TGF-beta1: This cytokine fuels systemic inflammation and disrupts regulatory T-cell function.
  • Abnormal MBL Pathway Activation: This pathway contributes to inflammation and can be detected through the CIRS blood test.
  • VEGF Levels: Abnormal levels of VEGF (Vascular Endothelial Growth Factor) can indicate blood-brain barrier disruption, potentially affecting the central nervous system.

CIRS Blood Test Thresholds:

  • MSH: > 36 pg/ml (levels below 36 may be associated with chronic fatigue syndrome)
  • VEGF: 31 – 86 (outside this range may be concerning)
  • MMP-9: < 332 ng/mL (levels above this are considered elevated)

Disclaimer: This information is for educational purposes only and does not constitute medical advice. Always consult your healthcare provider for diagnosis and treatment plans.

Further Resources:

  • Dr. Ritchie Shoemaker’s Paper: “Innate immunity, MR spectroscopy, HLA DR, TGF beta-1, VIP and capillary hypoperfusion define acute and chronic human illness acquired following exposure to water-damaged buildings.” This paper delves deeper into the science behind CIRS diagnosis and treatment.

By offering these specialized CIRS blood tests, Australia is taking a significant step towards better diagnosis and management of this complex condition.



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