At Last The Blood Tests Developed For Dr Ritchie Shoemaker Are Here in Australia

The following are blood tests developed for Dr Ritchie Shoemaker in looking at CIRS – Chronic Inflammatory Response Syndrome – can be carried out in Melbourne, these tests would be looking for elevated TGF?-1, C4-a, C3-a, and low levels of MSH and VIP, which may provide your physician with results which can be used to determine CIRS.

CIRS may not just be associated with your home but your work environment and all too often people do not recognise there is an issue until they have run out of medical opinions, so please understand microbial exposures can be hidden and bacterial contamination cannot be seen by the naked eye.

Affected individuals with CIRS patients lose control of inflammatory pathways as levels of regulatory neuropeptides VIP and MSH decline, further adding to the inflammatory burden. Abnormal activation of MBL pathway of complement (Wallis, 2008) and elevated TGF beta-1 (Vignali, 2008) add to systemic inflammation and loss of normal regulatory T-cell function, 4 respectively.

These tests will be offered shortly here in Australia once validation has been completed.

Understanding These Tests
VEGF – Vascular endothelial growth factor suggested greater than 31 or less than 86- Astrocyte-derived VEGF-A drives blood brain barrier disruption in CNS inflammatory disease (Journal of Clinical investigation 122 (2012) 2454-68)

MSH – Melanocyte stimulating hormone- suggested threshole is greater than 36-MSH below 36 pg/ml has been associated with those suffering from Chronic fatigue Syndrome pg/ml. This important molecule helps regulate the immune system

C4a – can alter the blood brain barrier

VIP – Vasoactive intestinal polypeptide

MMP – Matrix metalloproteinase 9 – it’s an inflammatory marker involved in many degenerative processes- any levels above 332 ng/mL is considered to be elevated

ADH -ADH determines how often we pee and how concentrated our urine is.

Naturally the above information is simply to provide some understanding which up until now has not really being available here in Australia, this in no way promotes a medical opinion and should be used in conjunction with your treating medical doctor.

For those who like to understand more you might like to search a current paper written by Dr Ritchie Shoemaker “Innate immunity, MR spectroscopy, HLA DR, TGF beta-1, VIP and capillary hypoperfusion define acute and chronic human illness acquired following exposure to water-damaged buildings.”

A copy of that paper’s summary is below.

SUMMARY
Progress in understanding host innate immune inflammatory responses has led to advances in diagnosis and treatment of patients with illness acquired following exposure to the interior environment of water-damaged buildings (WDB). Profiling cases compared to controls based on innate immunity abnormalities that are correlated with measures of capillary hypoperfusion resulted in accurate classification. WDB-illness is a complex syndrome of absent or deficient regulatory neuropeptides MSH and VIP, elevated C4a, TGF beta-1 cytokines and hormonal dysregulation. Use of symptom rosters, visual contrast sensitivity testing and genetic markers adds to diagnostic certainty. Treatment modalities that correct these abnormalities lead to symptom reduction and clinical improvement.

Cheers and Good Health
Vince Neil
Mycotox

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